[HTML][HTML] H and L ferritin subunit mRNA expression differs in brains of control and iron-deficient rats

J Han, JL Beard, JR Day, JR Connor - The Journal of nutrition, 2002 - Elsevier
The mRNA expression of ferritin subunits has not been studied thoroughly in the brain
regions of iron-deficient rats. Sprague-Dawley rats (n= 26; 21 d old) were randomly
assigned to an iron-deficient (3.5 mg Fe/kg diet) or a control diet (35 mg Fe/kg diet) for 6 wk.
Ferritin protein and mRNA contents were quantified and the cellular expression of ferritin
subunits in brain was determined. H and L ferritin had the same mRNA locations in nearly all
brain regions. Both ferritin subunit mRNAs had heterogeneous distributions and there was a …