Expression and regulation of antiviral protein APOBEC3G in human neuronal cells
YJ Wang, X Wang, H Zhang, L Zhou, S Liu… - Journal of …, 2009 - Elsevier
Apolipoprotein B mRNA-editing enzyme, catalytic polypeptide-like 3G (APOBEC3G) has
recently been identified as a potent antiviral protein. Here, we examined the expression and
regulation of APOBEC3G in human brain tissues and the cells of central nervous system
(CNS). Similar to the immune cells, human brain tissue and the CNS cells expressed
APOBEC3G at both mRNA and protein levels. The expression of APOBEC3G could be up-
regulated in human neuronal cells (NT2-N) and astrocytes (U87-MG) by interferons (IFN-α, β …
recently been identified as a potent antiviral protein. Here, we examined the expression and
regulation of APOBEC3G in human brain tissues and the cells of central nervous system
(CNS). Similar to the immune cells, human brain tissue and the CNS cells expressed
APOBEC3G at both mRNA and protein levels. The expression of APOBEC3G could be up-
regulated in human neuronal cells (NT2-N) and astrocytes (U87-MG) by interferons (IFN-α, β …