[HTML][HTML] Hematopoietic stem cell compartment: acute and late effects of radiation therapy and chemotherapy
P Mauch, L Constine, J Greenberger, W Knospe… - International Journal of …, 1995 - Elsevier
The bone marrow is an important dose-limiting cell renewal tissue for chemotherapy, wide-
field irradiation, and autologous bone marrow transplantion. Over the past 5–10 years a
great deal has been discovered about the hematopoietic stem cell compartment. Although
the toxicity associated with prolonged myelosuppression continues to limit the wider use of
chemotherapy and irradiation, ways are being discovered to circumvent this toxicity such as
with the increasing use of cytokines. This review describes what is known of how …
field irradiation, and autologous bone marrow transplantion. Over the past 5–10 years a
great deal has been discovered about the hematopoietic stem cell compartment. Although
the toxicity associated with prolonged myelosuppression continues to limit the wider use of
chemotherapy and irradiation, ways are being discovered to circumvent this toxicity such as
with the increasing use of cytokines. This review describes what is known of how …