[HTML][HTML] The macrophage C-type lectin specific for galactose/N-acetylgalactosamine is an endocytic receptor expressed on monocyte-derived immature dendritic cells
N Higashi, K Fujioka, K Denda-Nagai… - Journal of Biological …, 2002 - ASBMB
Lectins on antigen presenting cells are potentially involved in the antigen uptake and the
cellular recognition and trafficking. Serial analysis of gene expression in monocyte-derived
dendritic cells (DCs), monocytes, and macrophages revealed that 7 of the 19 C-type lectin
mRNA were present in immature DCs. Two of these, the macrophage mannose receptor and
the macrophage lectin specific for galactose/N-acetylgalactosamine (MGL), were found only
in immature DCs, as confirmed by reverse transcriptase-PCR and flow cytometric analysis …
cellular recognition and trafficking. Serial analysis of gene expression in monocyte-derived
dendritic cells (DCs), monocytes, and macrophages revealed that 7 of the 19 C-type lectin
mRNA were present in immature DCs. Two of these, the macrophage mannose receptor and
the macrophage lectin specific for galactose/N-acetylgalactosamine (MGL), were found only
in immature DCs, as confirmed by reverse transcriptase-PCR and flow cytometric analysis …
