The aqueous outflow system is unique because nowhere else can the pattern of flow of an
extravascular fluid be directly observed as it returns to the vascular system. Such
observations reveal that aqueous flow both from Schlemm's canal into the aqueous veins
and from the aqueous veins into the episcleral veins is pulsatile. Pulsatile aqueous flow
mechanisms are observable in vivo not only in normal and but also in glaucomatous eyes. A
series of specific patterns accompany the pulsatile mixing of aqueous with blood in the …