Impairing oral tolerance promotes allergy and anaphylaxis: a new murine food allergy model
K Ganeshan, CV Neilsen, A Hadsaitong… - Journal of Allergy and …, 2009 - Elsevier
BACKGROUND: Food allergy is a disorder in which antigenic food proteins elicit immune
responses. Animal models of food allergy have several limitations that influence their utility,
including failure to recapitulate several key immunologic hallmarks. Consequently, little is
known regarding the pathogenesis and mechanisms leading to food allergy.
Staphylococcus aureus–derived enterotoxins, a common cause of food contamination, are
associated with antigen responses in atopic dermatitis. OBJECTIVE: We hypothesized that S …
responses. Animal models of food allergy have several limitations that influence their utility,
including failure to recapitulate several key immunologic hallmarks. Consequently, little is
known regarding the pathogenesis and mechanisms leading to food allergy.
Staphylococcus aureus–derived enterotoxins, a common cause of food contamination, are
associated with antigen responses in atopic dermatitis. OBJECTIVE: We hypothesized that S …