MicroRNA expression patterns to differentiate pancreatic adenocarcinoma from normal pancreas and chronic pancreatitis

M Bloomston, WL Frankel, F Petrocca, S Volinia… - Jama, 2007 - jamanetwork.com
ContextWhile global microRNA (miRNA) expression patterns of many embryologic,
physiologic, and oncogenic processes have been described, description of the role of
miRNAs in ductal adenocarcinoma of the pancreas is lacking. ObjectiveTo define the
expression pattern of miRNAs in pancreatic cancer and compare it with those of normal
pancreas and chronic pancreatitis. Design and SettingSpecimens were obtained at a
National Cancer Institute–designated comprehensive cancer center from patients with ductal …