Extracellular calcium and cAMP: second messengers as “third messengers”?
AM Hofer, K Lefkimmiatis - Physiology, 2007 - journals.physiology.org
Physiology, 2007•journals.physiology.org
Calcium and cyclic AMP are familiar second messengers that typically become elevated
inside cells on activation of cell surface receptors. This article will explore emerging
evidence that transport of these signaling molecules across the plasma membrane allows
them to be recycled as “third messengers,” extending their ability to convey information in a
domain outside the cell.
inside cells on activation of cell surface receptors. This article will explore emerging
evidence that transport of these signaling molecules across the plasma membrane allows
them to be recycled as “third messengers,” extending their ability to convey information in a
domain outside the cell.
Calcium and cyclic AMP are familiar second messengers that typically become elevated inside cells on activation of cell surface receptors. This article will explore emerging evidence that transport of these signaling molecules across the plasma membrane allows them to be recycled as “third messengers,” extending their ability to convey information in a domain outside the cell.
American Physiological Society