Interferon-γ production by natural killer cells and cytomegalovirus in critically ill patients

L Chiche, JM Forel, G Thomas, C Farnarier… - Critical care …, 2012 - journals.lww.com
Objective: The mechanisms involved in cytomegalovirus reactivation in critically ill patients
who were previously immunocompetent are still unknown. The current study was designed
to evaluate the possible role of natural killer cells in the reactivation of cytomegalovirus in
these patients. Design: Prospective observational. Setting: A medical intensive care unit of a
university hospital. Patients: Fifty-one subjects, including 15 patients who experienced
cytomegalovirus reactivation (cases) during their intensive care unit stay and 15 patients …