Association of intravenous immunoglobulins plus methylprednisolone vs immunoglobulins alone with course of fever in multisystem inflammatory syndrome in …
N Ouldali, J Toubiana, D Antona, E Javouhey, F Madhi… - Jama, 2021 - jamanetwork.com
Importance Multisystem inflammatory syndrome in children (MIS-C) is the most severe
pediatric disease associated with severe acute respiratory syndrome coronavirus 2 infection,
potentially life-threatening, but the optimal therapeutic strategy remains unknown. Objective
To compare intravenous immunoglobulins (IVIG) plus methylprednisolone vs IVIG alone as
initial therapy in MIS-C. Design, Setting, and Participants Retrospective cohort study drawn
from a national surveillance system with propensity score–matched analysis. All cases with …
pediatric disease associated with severe acute respiratory syndrome coronavirus 2 infection,
potentially life-threatening, but the optimal therapeutic strategy remains unknown. Objective
To compare intravenous immunoglobulins (IVIG) plus methylprednisolone vs IVIG alone as
initial therapy in MIS-C. Design, Setting, and Participants Retrospective cohort study drawn
from a national surveillance system with propensity score–matched analysis. All cases with …