Association of mycobacterial antigen-specific CD4+ memory T cell subsets with outcome of pulmonary tuberculosis
X Wang, Z Cao, J Jiang, H Niu, M Dong, A Tong… - Journal of Infection, 2010 - Elsevier
OBJECTIVES: Memory T cells are hallmark of acquired immunological responses. The
relationship of mycobacterial antigen-specific CD4+ memory T cell subsets with pulmonary
tuberculosis was investigated. METHODS: The mycobacterial antigen-specific CD4+ T cells
were detected based on CD154 expression and phenotypes of memory T cell were
analyzed by surface staining of CD45RA and CCR7 and flow cytometrical analysis in
patients with pulmonary tuberculosis and in tuberculin-positive healthy controls. The …
relationship of mycobacterial antigen-specific CD4+ memory T cell subsets with pulmonary
tuberculosis was investigated. METHODS: The mycobacterial antigen-specific CD4+ T cells
were detected based on CD154 expression and phenotypes of memory T cell were
analyzed by surface staining of CD45RA and CCR7 and flow cytometrical analysis in
patients with pulmonary tuberculosis and in tuberculin-positive healthy controls. The …