Deep brain stimulation of the nucleus accumbens reduces ethanol consumption in rats
CM Knapp, L Tozier, A Pak, DA Ciraulo… - Pharmacology …, 2009 - Elsevier
Recent studies have shown that deep brain stimulation (DBS) of the nucleus accumbens
(NAcc) has an inhibitory effect on drug-seeking behaviors including reinstatement
responding for cocaine. The objective of the present study was to expand on these findings
by assessing the effects of DBS on behaviors related to alcohol consumption. The specific
aim of this study was to determine whether DBS delivered to either the shell or core of the
NAcc would reduce ETOH intake in rats using a two-bottle choice limited access procedure …
(NAcc) has an inhibitory effect on drug-seeking behaviors including reinstatement
responding for cocaine. The objective of the present study was to expand on these findings
by assessing the effects of DBS on behaviors related to alcohol consumption. The specific
aim of this study was to determine whether DBS delivered to either the shell or core of the
NAcc would reduce ETOH intake in rats using a two-bottle choice limited access procedure …
