Timing of onset of CKD-related metabolic complications
O Moranne, M Froissart, J Rossert… - Journal of the …, 2009 - journals.lww.com
Chronic kidney disease (CKD) guidelines recommend evaluating patients with GFR< 60
ml/min per 1.73 m 2 for complications, but little evidence supports the use of a single GFR
threshold for all metabolic disorders. We used data from the NephroTest cohort, including
1038 adult patients who had stages 2 through 5 CKD and were not on dialysis, to study the
occurrence of metabolic complications. GFR was measured using renal clearance of 51 Cr-
EDTA (mGFR) and estimated using two equations derived from the Modification of Diet in …
ml/min per 1.73 m 2 for complications, but little evidence supports the use of a single GFR
threshold for all metabolic disorders. We used data from the NephroTest cohort, including
1038 adult patients who had stages 2 through 5 CKD and were not on dialysis, to study the
occurrence of metabolic complications. GFR was measured using renal clearance of 51 Cr-
EDTA (mGFR) and estimated using two equations derived from the Modification of Diet in …